Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1997-04-09
2000-02-01
Fitzgerald, David L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
424 856, 424 857, 435 6951, C07K 1456, A61K 3821, C12N 1521
Patent
active
060204656
ABSTRACT:
The present invention relates to a chicken interferon gene coding for the amino acid sequence of SEQ ID NO: 2. The present invention also relates to a method of producing chicken interferon recombinantly, a method of isolating other non-mammalian interferon genes, a method of making a transgenic fowl having the chicken interferon gene incorporated therein, and method for delivery of the chicken interferon in the bird, such as by genetic immunization or aerosol. Expression of the chicken IFN gene yields functional chicken interferon.
REFERENCES:
patent: 4289690 (1981-09-01), Pestra et al.
Salter, Donald W. et al., "Transgenic Chickens: Insertion of Retroviral Genes into the Chicken Germ Line," Virology, 157:236-240 (1987).
Salter, Donald W. et al., "Lack of genetic transmission of avian leukosis proviral DNA in viremic Japanese quall," (Abstract) Proceedings of the Second Symposium on Genetic Engineering of Animals, Cornell University, Ithaca, NY (1989). Journal of Reproduction and Fertility, Supplement 41 (1990).
Fernando, Lawrence P. and Andrews Glen K., "Cloning and expression of an avian methallothionein-encoding gene," Gene, 81:177-183 (1989).
Marcus, Philip I. and Sekellick, Margaret J., "Interferon Induction by Viruses. XVI. 2-Aminopurine Blocks Selectively and Reversibly an Early Stage in Interferon Induction," J. Gen. Virol., 69:1637-1645 (1988).
Svitlik, Charles and Marcus, Philip I., "Interferon Induction by Virusus. XII. Inhibition of Protein Synthesis Renders Aged Chick Embryo Cells Refractory to Interferon Induction," J. Gen. Virol., 66:883-886 (1985).
Sekellick, Margaret J. and Marcus, Philip I., "Inferferon Induction by Viruses. XIV. Development of Interferon Inducibility and Its Inhibition in Chick Embryo Cells "Aged" In Vitro," Journal of Interferon Research, 5:651-667 (1985).
Sekellick, Margaret J. and Marcus, Philip I., "Induction of High Titer Chicken Interferon," Methods in Enzymology, 119:115-125 (1986).
Yoshida, Itsuroand Marcus, Philip I., "Interferon Induction by Viruses. XX. Acid-Labile Interferon Accounts for the Antiviral Effect Induced by Poly(rI).cndot.Poly(rC) in Primary Chick Embryo Cells," Journal of Interferon Research, 10:461-468 (1990).
Marcus, Philip I. et al., "Interferon Induction by Viruses. XII. Vesicular Stomatitis Virus: Interferon Inducibility as a Phylogenetic Marker," Journal of Interferon Research, 12:297-305 (1992).
Sekellick, Margaret J. et al., "Development of the Interferon System. I. In Chicken Cells Development in Ovo Continues on Time In Vitro," In Vitro Cell. Dev. Biol., 26:997-1003 (1990).
Hough, S. and R.H. Foote, "The Effect of the Cornell Particle Gun on Bull and Rabbit Spermatozoa," Abstract, Biology of Reproduction, 42:65 (1990).
Crittenden, L.B. and Salter, D.W., "Expression and mobility of retroviral inserts in the chicken germ line," Transgenic Models in Medicine and Agriculture, pp. 73-87, Wiley-Liss, Inc. (1990).
Reed, M.L. et al., "Microinjection of liposome-encapsulated DNA into murine and bovine blastocysts," Abstract, Theriogenology, 29(1):293 (1988).
Coonrod, S.A. et al., "Successful non-surgical collection of ovine embryos," Abstract, Theriogenology, 25(1):149 (1986).
Shuman, R.M. et al., "Tissue specificity of a retrovirus gene transfer vector revealed by expression of a bacterial marker gene," Abstracts of the 9th Annual Meeting of The Southern Poultry Science Society, Poultry Science, 67, Supplement 1:156 (1988).
Shuman, R.M. , "Use of retrovirus vectors for gene insertion in poultry and swine," J. of Dairy Sci., 72(suppl. 1):61 (1989).
Sekellick, Margaret J. et al., "Chicken Interferon Gene: Cloning, Expression, and Analysis," Journal of Interferon Research, 14:83-91 (1994).
Shuman, R.M., "Production of transgenic birds," Experientia 47(9):897-905 (1991).
Tamai, Tadakazu et al., "Cloning and expression of flatfish (Paralichthys olivaceus) interferon cDNA," Biochimica et Biophysica Acta 1174(2):182-186 (1993).
Sekellick, Margaret J. et al., "Chicken Interferon cDNA Probe," Journal of Interferon Research 13, Suppl. 1:S68, Abstract PW1-2 of The 1993 Annual Meeting of the ISICR, Tokyo, Japan (1993).
Krempien, Ursula et al., "Purification of Chick Interferon by Zinc Chelate Affinity Chromatography and Sodium Dodecylsulfate-Polyacrylamide Gel Electrophoresis," Journal of Interferon Research 5(1):209 214 (1985).
Kohase, Masayoshi et al., "Purification and Characterization of Chick Interferon Induced by Viruses," J. Gen Virol. 67(1):215-218 (1986).
Guggenhein, M.A., et al. (1988) Science 159: 542-43.
Klasing, K.C. (1994) Poultry Sci. 73:1035-43.
Ferrandino Anthony F.
Marcus Philip I.
Sekellick Margaret J.
Fitzgerald David L.
University of Connecticut
LandOfFree
Recombinant avian type i interferon does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant avian type i interferon, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant avian type i interferon will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-938675