Recombinant aprotinin variants genetically engineered process fo

Details Recombinant aprotinin variants genetically engineered process fo Recombinant aprotinin variants genetically engineered process fo

1992-06-25

1993-07-27

Schain, Howard E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

530324, C12N 1515, C07K 710, C07K 1504

Patent

active

052310108

ABSTRACT:
An aprotinin with a deletion of the amino acid proline in position 2 or an addition of alanine-(-2)-glutamine-(-1). Such aprotinin is useful as an active ingredient in medicaments.

REFERENCES:
patent: 5032573 (1991-07-01), Auerswald et al.
patent: 5118668 (1992-06-01), Auerswald et al.
patent: 5122594 (1992-06-01), Yoshida et al.
patent: 5126322 (1992-06-01), Collins et al.
patent: 5164482 (1992-11-01), Ebbers et al.

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