Recombinant antigen MSP1a from anaplasma marginale to reduce...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

Reexamination Certificate

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C424S266100, C424S184100, C424S191100, C424S093100

Reexamination Certificate

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06979451

ABSTRACT:
Vaccines and methods for inducing an immune response in a ruminant. The vaccine composition including pathogen and tick-derived antigens and a carrier or diluent. The method for inducing an immune response in a ruminate to provide immune protection which reduces the infection of ticks byA. marginaleand/or prevents the transmission of the pathogen includes the steps of administering to the ruminant an effective amount of the vaccine composition having at least one antigen member of the group comprising at least one antigen member of the group comprising (i) recombinant MSP1a surface protein antigen ofA. marginale, (ii) a subunit of recombinant MSP1a surface protein antigen ofA. marginaleand (iii) recombinant MSP1a surface protein antigen or subunits thereof in combination with antigen preparation derived fromA. marginaleinfected cultured tick IDE8 cells and/or other pathogen and tick-derived antigens, and a carrier or diluent.

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