Recombinant antigen from the NS3 region of the hepatitis C virus

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4241891, 435 5, 435 72, 435 693, 530300, 530350, A61K 3929, C12Q 170

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active

060963190

ABSTRACT:
The present invention concerns a polypeptide which is composed of the amino acids 1207.+-.10 to 1488.+-.10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.

REFERENCES:
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Eisenlohr et al. The Journal of Experimental Medicine 175: 481-487, Feb. 1992.
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Reeck 1987 Cell vol. 50, p 667.
Purcell "Hepatitis Virus" In Encyclopedia of Virology vol. 2, Webster & Granoff Eds., Academic Press, Harcourt Brace & Comp., publishers, New York, p. 569-574, 1994.
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Choo et al. PNAS (USA) 88: 2451-2455, 1991.
Yang et al., Science in China (Series B) 37(2): 190-202, Feb. 1994.

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