Recombinant antibodies for human therapy

Details Recombinant antibodies for human therapy Recombinant antibodies for human therapy

1995-06-07

1998-05-26

Feisee, Lila

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241331, 4241411, 5303871, A61K 39395

Patent

active

057560960

ABSTRACT:
Chimeric antibodies including an Old World monkey portion and a human portion, nucleic acid encoding such antibodies, Old World monkey monoclonal antibodies, and methods for their production and use.

REFERENCES:
patent: 4816397 (1989-03-01), Boss et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4973745 (1990-11-01), Schoemaker et al.
patent: 4975369 (1990-12-01), Beavers et al.
Moreland et al, 1991. J Cell Biochem Suppl 15(Paul-E) 183. Meeting on Molecular Biology and the immunopathogeneses of Rheumatoid Arthritis 20th Annual Meeting of Keystone Symposia on Mol. & Cell Biol. Mar. 15-21, 1991.
Herzog et al J of Autoimmunity, vol. 2 (5) 627-42, 1989, Oct.
Dillman et al 1989 Annals of Internal Medicine vol. 111 No. 7 pp. 592-600 1, Oct. 1989.
Rosenberg, M. et al., Biotheraphy, "Soluble Recombinant CD4-A Potential Therapeutic Agent for HIV Infector"2:107, (1990).
Riechmann, L. et al., Nature, "Reshaping Human Antibodies for Therapy", 332:323-327, (1988).
Houghton, A.N. et al., Seminars in Oncology, "Monoclonal Antibodies Potential Applications to the Treatment of Cancer", 13:165, (1986).
Watanabe, M. et al., Proceedings of the National Academy of Sciences, 88:4616-4620, (1991).
Letvin, et al., Effect of Recombinant Soluble CD4 in Rhesus Monkeys Infected with Simian Immunodeficient Virus of Macagues Abstract from the V. Int. Conf. on AIDS, p. 535, (1989).
BS Heteromycloma line, abstract.
Herpes Transformation, abstract.
Morrison, Science vol. 229, pp. 1202 (1985).
Queen et al., NAS 8610029 (1989).
Waldmann, Science vol., 252, pp. 1657 (1991).
Sharp, RM et al., 126 J. Imm. Methods 287 (1990).
Ehrlich, PH et al., 28 Mol. Immun. 319 (1991).
Groves, DJ & Tucker, EM 23 Vet. Immuno. and Imunopath. 1 (1989).
Stanley, HA & Reese, RT 82 PNAS 6272 (1985).
VOPR VIRUSOL, vol. 30, No. 5, issued Oct. 1985, Markova et al., "Monkey B lymphocyte subpopulations transformed by baboon herpes virus in vivo and in tissue cultures", pp. 549-553.
Harris et al., T. B. Tech., vol. 11, p. 42 (1993).
Truneh et al., "Humoral Response of Cynomolgus Macaques to Human Soluble CD4: Antibody Reactivity Restricted to Xeno-Human Determinants", Cellular Immunology, vol. 131, No. 1, pp. 88-108 (Nov. 1990).
Van Meurs et al., "Production of Primate Monoclonal Antibodies", Journal Or Immunological Methods, 1986, vol. 95, pp. 123-128.
Schroeder et al., "Early Restriction of the Human Antibody Repertoire", Science, vol. 238, pp. 791-793. (Nov. 6, 1987).
Combriato et al., "V Lambda and J Lambda-C Lambda Gene Segments of the Human Immunoglobulin Lambda Light Chain Locus are Separated by 14 KB and Rearrange by a Deletion Mechanism", European Journal Or Immunology, vol. 21, pp. 1513-1522 (Jun. 1991).
Hughes-Jones et al., "Nucleotide Sequences and Three-Dimensional Modelling of the VH and VL Domains of Two Human Monoclonal Antibodies Specific for the D Antigen of the Human RH-Blood Group System", The Biochemical Journal, vol. 268, No. 1, pp. 135-140 (May 15, 1990).
Stephens et al., "Antibodies are Produced to the Variable Regions of the External Envelope Glycoprotein of Human Immunodeficiency Virus Type 1 in Chimpanzees Infected with the Virus and Baboons Immunized with a Candidate Recombinant Vaccine", The Journal of General Virology, vol. 73, No. 5, pp. 1099-1106 (May 1992).
Amoroso et al., J. Immun., Herpes Transformation, abstract, 145:3155 (1990).
Huse et al., Science, BS Heteromycloma Line, abstract, 246:1275 (1989).
Ehrlich et al., Hum. Antibod. Hybridomas, vol. 1, No. 1(1990).
Ehrlich et al., Hybridoma, vol. 7, No. 4, pp. 385-395 (1988).
Ehrlich et al., Hybridoma, vol. 6, No. 2, pp. 151-160 (1987).
Ehrlich et al., Clin. Chem., 34:1681 (1988).
Van Meel et al., J. Immunological Methods, 80:267 (1985).
Persson et al., Proc. Natl. Acad. Sci. USA, 88:2432 (1991).
Meek et al., J. Immun., 146:2434 (1991).
Allison et al., J. Immunological Methods, 95:157 (1986).
Nishimura, Y. et al., Cancer Research, 47:999 (1987).
Ward, E.S. et al., Nature, 341:544 (1989).
McClure, M. O. et al., Nature, 330:487 (1987).
Truneh, A. et al., Cell Immun., 131:98 (1990).
Camerini, D. and Seed, B., Abstract No. T.C.P. 125, V International Conference on AIDS, p. 587 (1989).
Camerini, D. and Seed, B., Cell, 60:747 (1990).
Jones, P.T., et al., Nature, 321:522 (1986).

Affiliated with

Also associated with

Rating

Recombinant antibodies for human therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant antibodies for human therapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant antibodies for human therapy will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1957286