Recombinant antibodies for human therapy

Details Recombinant antibodies for human therapy Recombinant antibodies for human therapy

1995-01-25

1997-08-19

Feisee, Lila

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

53038822, 435 7021, 4351722, 4351723, 435 696, 935 96, C07K 1628, A61K 3938, C12P 2104

Patent

active

056585705

ABSTRACT:
Chimeric antibodies including an Old World monkey portion and a human portion, nucleic acid encoding such antibodies, Old World monkey monoclonal antibodies, and methods for their production and use.

REFERENCES:
patent: 4816397 (1989-03-01), Boss et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4973745 (1990-11-01), Schoemaker et al.
patent: 4975369 (1990-12-01), Beavers et al.
Letvin, et al., Effect of Recombinant Soluble CD4 in Rhesus Monkeys Infected With Simian Immunodeficiency Virus of Macaques Abstract from the V Int. Conf. an AIDS, 1989, p. 535.
Watanabe, M. et al., Proceedings of the National Academy of Sciences, 88:4616-4620, (1991).
Rosenberg, M. et al., Biotherapy, "Soluble recombinant CD4--A potential therapeutic agent for HIV infector", 2:1107, (1990).
Riechmann, L. et al., Nature, "Reshaping human antibodies for therapy", 332:323-327, (1988).
Houghton, A.N. et al., Seminars in Oncology, "Monoclonal antibodies:potential applications to the treatment of cancer", 13:165, (1986).
Herpes Transformation, abstract 1985.
Amoroso et al., J. Immun., 145:3155, 1990.
Huse et al., Science, 246:1275, 1989.
BS Heteromycloma line, abstract 1986.
Ehrlich et al., Hum. Antibod. Hybridomas, 1990, vol. 1, No. 1.
Ehrlich et al., Hybridoma, vol. 6, No. 2, pp. 151-160, 1987.
Ehrlich et al., Hybridoma, vol. 7, No. 4, pp. 385-395, 1988.
Ehrlich et al., Clin. Chem., 34:1681, 1988.
Van Meel et al., J. Immunological Methods., 80:267, 1985.
Persson et al., Proc. Natl. Acad. Sci. USA, 88:2432, 1991.
Meek et al., J. Immun., 146:2434, 1991.
Allison et al., J. Immunological Methods, 95:157, 1986.
Nishimura, Y. et al., Cancer Research, 47:999 (1987).
Ward, E.S. et al., Nature, 341:544 (1989).
Camerini, D. and Seed, B., Abstract No. T.C.P. 125, V International Conference on AIDS, p. 587, (1989).
Camerini, D. and Seed, B., Cell, 60:747, (1990).
McClure, M.O. et al., Nature, 330:487, (1987).
Truneh, A. et al., Cell. Immun., 131:98 (1990).
Jones, P.T. et al., Nature, 321:522, (1986).
Harris et al. Tibtech vol. 11 p. 42, 1993.
Van Meurz et. al. Journal of Immunological Methods 95(1985) 123-128.
Morrison Science vol. 229. 1202, 1985 Immunology Today 10:253 (1989).
Queen et al. PNAS 8610029 (1989).
Waldmann Science vol. 252, 1657 1991.
Hird et. al. Genes and Cancer 1990 183.
Sharp, RM et al. 126 J.Imm.Methods 287 (1990) Feb. 4, 1994.
Ehrlich, PH et al. 28 Mol.Immun. 319 (1991) Feb. 4, 1994.
Groves, DJ & Tucker, EM 23 Vet.Immuno. and Imunopath.1 (1989) Feb. 4, 1994.
Stanley, HA & Resse, RT 82 PNAS 6272 (1985) Feb. 4, 1994.
Schroeder et al. "Early Restriction of the Human Antibody Repertoire" Science, Nov. 6, 1987, vol. 238, pp. 791-793.
Combriato et al. "V Lambda and J Lambda-C Lambda Gene Segments of the Human Immunoglobulin Lambda Light Chain Locus are Separated by 14 KB and Rearrange by a Deletion Mechanism" European Journal of Immunology, Jun. 1991, vol. 21, pp. 1513-1522.
Hughes-Jones et al. "Nucleotide Sequences and Three-Dimensional Modelling of the VH and VL of Two Human Monoclonal Antibodies Specific for the D Antigen of the Human RH-Blood Group System" The Biochemical Journal, May 15, 1990, vol. 268, No. 1, pp. 135-140.
Stephens et al. "Antibodies are Produced to the Varible Regions of the External Envelope Glycoprotein of Human Immunodeficiency Virus Type 1 in Chimpanzees Infected with the Virus and Baboons Immunized with a Candidate Recombinant Vaccine" The Journal of General Virology, May 1992, vol. 73, No. 5, pp. 1099-1106.

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