Recombinant antibodies for human therapy

Details Recombinant antibodies for human therapy Recombinant antibodies for human therapy

1995-06-07

1997-10-28

Feisee, Lila

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 2353, 536 2432, 435 697, 435 912, 435 6, 5303873, C12P 2108, C12P 2104, C12P 1934, C07H 2104

Patent

active

056817223

ABSTRACT:
Chimeric antibodies including an Old World monkey portion and a human portion, nucleic acid encoding such antibodies, Old World monkey monoclonal antibodies, and methods for their production and use.

REFERENCES:
patent: 4816397 (1989-03-01), Boss et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4973745 (1990-11-01), Schoemaker et al.
patent: 4975369 (1990-12-01), Beavers et al.
Sommer et al. Nucleic Acids Research vol. 17, No. 16 1989. 6749.
Orland et al. PNAS 86 pp. 3833-3837 1989.
Rosenberg, M. et al., Biotheraphy, "Soluble Recombinant CD4 --A Potential Therapeutic Agent for HIV Infector", 2:107, (1990).
Riechmann, L. et al., Nature, "Reshaping Human Antibodies for Therapy", 332:323-327, (1988).
Houghton, A.N. et al., Seminars in Oncology, "Monoclonal Antibodies Potential Applications to the Treatment of Cancer", 13:165, (1986).
Watanabe, M. et al., Proceedings of the National Academy of Sciences, 88:4616-4620, (1991).
Letvin, et al., Effect of Recombinant Soluble CD4 in Rhesus Monkeys Infected with Simian Immunodeficient Virus of Macagues Abstract from the V. Int. Conf. on AIDS, p. 535, (1989).
BS Heteromycloma line, abstract.
Herpes Transformation, abstract.
Morrison, Science Vol. 229, p. 1202 (1985).
Queen et al., NAS 8610029 (1989).
Waldmann, Science Vol., 252, p. 1657 (1991).
Sharp, RM et al., 126 J. Imm. Methods 287 (1990).
Ehrlich, PH et al., 28 Mol. Immun. 319 (1991).
Groves, DJ & Tucker, EM 23 Vet. Immuno. and Imunopath. 1 (1989).
Stanley, HA & Reese, RT 82 PNAS 6272 (1985).
Vopr Virusol, vol. 30, No. 5, issued Oct. 1985, Markova et al., "Monkey B lymhocyte subpopulations transformed by baboon herpes virus in vivo and in tissue cultures", pp. 549-553.
Harris et al., T. B Tech., vol. 11, p. 42 (1993).
Truneh et al., "Humoral Response of Cynomolgus Macaques to Human Soluble CD4: Antibody Reactivity Restricted to Xeno-Human Determinants", Cellular Immunology, vol. 131, No. 1, pp. 98-108 (Nov. 1990).
Van Meurs et al., "Production of Primate Monoclonal Antibodies", Journal Or Immunological Methods, 1986, vol. 95, pp. 123-128.
Schroeder et al., "Early Restriction of the Human Antibody Repertoire", Science, vol. 238, pp. 791-793. (Nov. 6, 1987).
Combriato et al., "V Lambda and J Lambda-C Lambda Gene Segments of the Human Immunoglobulin Lambda Light Chain Locus are Separated by 14 KB and Rearrange by a Deletion Mechanism", European Journal Or Immunology, vol. 21, pp. 1513-1522 (Jun. 1991).
Hughes-Jones et al., "Nucleotide Sequences and Three-Dimensional Modelling of the VH and VL Domains of Two Human Monoclonal Antibodies Specific for the D Antigen of the Human RH-Blood Group System", The Biochemical Journal, vol. 268, No. 1, pp. 135-140 (May 15, 1990).
Stephens et al., "Antibodies are Produced to the Variable Regions of the External Envelope Glycoprotein of Human Immunodeficiency Virus Type 1 in Chimpanzees Infected with the Virus and Baboons Immunized with a Candidtate Recombinant Vaccine", The Journal Of General Virology, vol. 73, No. 5, pp. 1099-1106 (May 1992).
Amoroso et al., J. Immun., Herpes Transformation, abstract, 145:3155 (1990).
Huse et al., Science, BS Heteromycloma Line, abstract, 246:1275 (1989).
Ehrlich et al., Hum. Antibod. Hybridomas, vol. 1, No. 1 (1990).
Ehrlich et al., Hybridoma, vol. 7, No. 4, pp. 385-395 (1988).
Ehrlich et al., Hybridoma, vol. 6, No. 2, pp. 151-160 (1987).
Ehrlich et al., Clin. Chem., 34:1681 (1988).
Van Meel et al., J. Immunological Methods, 80:267 (1985).
Persson et al., Proc. Natl. Acad. Sci. USA, 88:2432 (1991).
Meek et al., J. Immun., 146:2434 (1991).
Allison et al., J. Immunological Methods, 95:157 (1986).
Nishimura, Y. et al., Cancer Research, 47:999 (1987).
Ward, E.S. et al., Nature, 341:544 (1989).
McClure, M. O. et al., Nature, 330:487 (1987).
Truneh, A. et al., Cell Immun., 131:98 (1990).
Camerini, D. and Seed, B., Abstract No. T.C.P. 125, V International Conference on AIDS, p. 587 (1989).
Camerini, D. and Seed, B., Cell, 60:747 (1990).
Jones, P.T., et al., Nature, 321:522 (1986).

Affiliated with

Also associated with

Rating

Recombinant antibodies for human therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant antibodies for human therapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant antibodies for human therapy will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1025446