Recombinant adenoviruses, use thereof for preparing AAVS,...

Details Recombinant adenoviruses, use thereof for preparing AAVS,... Recombinant adenoviruses, use thereof for preparing AAVS,...

2006-04-25

2006-04-25

Guzo, David (Department: 1636)

Chemistry: molecular biology and microbiology

Vector, per se

C536S023100, C536S023700, C536S023720, C536S024100

Reexamination Certificate

active

07033826

ABSTRACT:
A recombinant adenovirus in which the expression of a nucleic acid sequence coding for at least one homologous or heterologous gene of viral origin is placed under the control of an inducible promoter, is disclosed. The use of such recombinant adenoviruses for preparing AAVs, and a complementary cell line and preparation method therefor, are also disclosed. Furthermore, pharmaceutical compositions containing such an adenovirus are disclosed.

REFERENCES:
patent: 5639661 (1997-06-01), Welsh et al.
patent: 5698443 (1997-12-01), Henderson et al.
patent: 5756283 (1998-05-01), Wilson et al.
patent: 5814618 (1998-09-01), Bujard et al.
patent: 6110744 (2000-08-01), Fang et al.
patent: 2 707 664 (1995-01-01), None
patent: WO 94/12649 (1994-06-01), None
patent: WO 94/28152 (1994-12-01), None
patent: WO 95/02697 (1995-01-01), None
patent: WO 95/06743 (1995-03-01), None
patent: WO 95/20671 (1995-08-01), None
patent: WO 95/23867 (1995-09-01), None
patent: WO 96/01313 (1996-01-01), None
Kremer et al., Adenovirus and adeno-associated virus mediated gene transfer, British Medical Bulletin 51(1):31-44 (1995).
Ko et al., A Highly Inducible System of Gene Expression by Positive Feedback Production of Glucocorticoid Receptors, DNA 8(2): 127-134 (1989).
Gossen et al., Exploiting Prokaryotic Elements For The Control Of Gene Activity In Higher Eukaryotics, JournalCellular biochemistry Suppl. 21 A:335 (1995).
Deuschle et al., Tetracycline-Reversible Silencing of Eukaryotic Promoters, Molecular & Cellular Biology 15(4): 1907-1914 (1995).
Kim et al., Tetracycline Repressor-Regulated Gene Repression in Recombinant Human Cytomegalovirus, Journal of Virology 69(4): 2565-2573 91995).
Rolling et al., AAV as a Viral Vector for Human Gene Therapy, Molecular Biotechnology 3(1):9-15 (1995).
Hersh et al., Modulation of gene expression after replication-deficient, recombinant adenovirus-mediated gene transfer by the product of a second adenovirus vector, Gene Therapy 2(2): 124-131 (1995).
Gossen et al., Transcriptional Activation by Tetracyclines in Mammalian Cells, Science 268: 1766-1769 (1995).
W. French Anderson, Nature, vol. 392, pp. 25-30, Apr. 30, 1998.
Ross et al., Human Gene Therapy, vol. 7, pp. 1781-1790, Sep. 10, 1996.
Verma et al., Nature, vol. 389, pp. 239-242, Sep. 18, 1997.
Zhang et al., PNAS, vol. 93, pp. 4513-4518, Apr. 1996.
Orken et al., “Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy,” Dec. 7, 1995.
Siders et al., Cancer Research, vol. 56, pp. 5638-5646, Dec. 15, 1996.
Tanaka et al., Cancer Research, vol. 56, pp. 1341-1345, Mar. 15, 1996.
Boucher, TIG, vol. 12, No. 3, pp. 81-84, Mar. 1996.

Affiliated with

Also associated with

Rating

Recombinant adenoviruses, use thereof for preparing AAVS,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant adenoviruses, use thereof for preparing AAVS,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant adenoviruses, use thereof for preparing AAVS,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3595206