Recombinant adenovirus vector having a reduced side effect

Chemistry: molecular biology and microbiology – Vector – per se

Reexamination Certificate

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C424S093200, C424S093600, C514S04400A, C435S235100

Reexamination Certificate

active

07445929

ABSTRACT:
The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.

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