Recombinant adenovirus

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4241991, 4353201, 4352351, 435325, 435 691, A61K 39235, A61K 3912, C12N 700, C12N 701, C12N 1500

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active

061139130

ABSTRACT:
The present invention provides a recombinant adenovirus having a genome with a deficiency in the E1 region and a mutation in the MLP. The invention also provides stocks of such viruses and compositions including the inventive viruses. The invention also provides cell lines for propagating the recombinant adenoviruses.

REFERENCES:
patent: 4510245 (1985-04-01), Cousens et al.
patent: 5474935 (1995-12-01), Chatterjee et al.
Amalfitano et al. Proc. Natl. Acad. Sci. USA, 93, pp. 3352-3356 (1996).
Amalfitano et al. Gene Therapy, 4,pp. 258-263 (1997).
Amalfitano et al. Journal of Virology, 72(2), pp. 926-933 (1998).
Brunet et al. Molecular and Cellular Biology, 7(3), pp. 1091-1100 (1987).
Chodosh et al. Molecular and Cellular Biology, 6(12),pp. 4723-4733 (1986).
Gustin et al. Journal of Virology, 70(9), pp. 6463-6467 (1996).
Kubo et al. Gene, 153, pp. 279-280 (1995).
Loh et al. Journal of Biological Chemistry, 271(18), pp. 10884-10891 (1996).
Lu et al. Journal of Virology, 71(1), pp. 102-109 (1997).
Lutz et al. Journal of Virology, 70(3), pp. 1396-1405 (1996).
Lutz et al. Journal of Virology, 70(6), pp. 3449-3460 (1996).
Manohar et al. Journal of Virology, 64(6), pp. 2457-2466 (1990).
Miyamoto et al. The EMBO Journal, 4(13A), pp. 4563-3570 (1985).
Perlmutter et al. Clinical and Experimental Pharmacology and Physiology, 17, pp. 697-706 (1990).
Reach et al. Journal of Virology, 64(12), pp. 5851-5860 (1990).
Reach et al. The EMBO Journal, 10(11), pp. 3439-3446 (1991).
Sawadago et al. Cell, 43, pp. 165-175 (1985).
Schaack et al. Journal of Virology, 69(7), pp. 4079-4085 (1995).
Song et al. Virology, 220(2), pp. 390-401 (1996).
Strubin et al. Cell, 68, pp. 721-730 (1992).
Tribouley et al. Journal of Virology, 68(7), pp. 4450-4457 (1994).
Van Beveren et al. Gene, pp. 179-189 (1981).
Wilkinson et al. Nucleic Acids Research, 20(9), pp. 2233-2239 (1992).
Wu et al. Biotechniques, 21, pp. 718-725 (1996).
Lieber et al., Journal of Virology, 70 (12), 8944-8690 (1996).
Tansey et al., Science, 275 (5301), 829-831 (1997).
Yang et al., PNAS USA, 91 (10), 4407-4411 (1994).

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