Receptors

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4352401, 4353201, 536 231, 536 234, C12P 2106, C12N 500, C12N 1500, C07H 1700

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active

055716962

ABSTRACT:
Novel members of the steroid/thyroid superfamily of receptors are described. DNA sequences encoding same, expression vectors containing such DNA and host cells transformed with such expression vectors are also disclosed, as are methods for the expression of the novel receptors of the invention, and various uses thereof.

REFERENCES:
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patent: 5071773 (1991-12-01), Evans et al.
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Nathans et al., "Molecular Genetics of Human Color Vision: The Genes Encoding Blue, Green, and Red Pigments", Science vol. 232:193-202 (1986).
Hamada et al., "H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response element," Proc. Natl. Acad. Sci. USA vol. 86:8289-8293 (1989).
Tautz and Pfeifle, "A non-radioactive in situ hybidization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback," Chromosoma vol. 98:81-85 (1989).
Giguere et al., "Identification of a receptor for the morphogen retinoic acid," Nature vol. 330:624-629 (1987).
Evans, Ronald M., "The Steroid and Thyroid Hormone Receptor Superfamily," Science vol. 240:889-895 (1988).
Umesono et al 1991 Cell 65:1255-1266.
Umesono & Evans 1989 Cell 57:1139-1146.
Umesono et al. 1988 Nature 336:262-265.

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