Receptor-type phosphotyrosine phosphatase-alpha

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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435 691, 435 698, 435 701, 435 712, 435196, 4352523, 4352542, 4351723, 4353201, 435 6, 536 231, 536 232, 935 14, 935 27, 935 56, 935 69, 935 70, 935 72, C12N 1555, C12N 1563, C12N 121, C12N 510

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055388868

ABSTRACT:
A novel receptor-type protein tyrosine phosphatase (RPTP) protein or glycoprotein and the DNA coding therefor is expressed in a wide variety of mammalian tissues. Included in this family of proteins are human RPTP.alpha., human RPTP.beta. and human RPTP.gamma.. The RPTP protein or glycoprotein may be produced by recombinant means. Antibodies to the proteins, methods for measuring the quantity of the proteins, methods for screening compounds, such as drugs, which can bind to the proteins and inhibit or stimulate their activity, are provided.

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