Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Patent
1995-01-17
2000-07-11
Cunningham, Thomas M.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
4241781, 5303871, 53038822, A61K 39385, A61K 3944
Patent
active
060868759
ABSTRACT:
Methods and products for modulating an immune response are provided. Pharmaceutical preparations contain a conjugate of an antigen and a FcRn binding partner. The conjugates are administered to mammals in effective amounts to modulate the immune system by stimulating the immune response against the antigen or tolerizing the immune system to the antigen. The antigen may be characteristic of a pathogen, of an autoimmune disease or of an allergen.
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Blumberg Richard S.
Lencer Wayne L.
Simister Neil E.
Brandeis University
Cunningham Thomas M.
The Brigham and Women's Hospital, Inc.
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