Receptor for the glucagon-like-peptide (GLP-1)

Details Receptor for the glucagon-like-peptide (GLP-1) Receptor for the glucagon-like-peptide (GLP-1)

1997-09-22

2000-04-18

Fitzgerald, David L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

435 691, C07K 1472, C12N 1512

Patent

active

060516895

ABSTRACT:
The present invention relates to a recombinant glucagonlike peptide-1 (GLP-1) receptor having the nucleotide sequence of SEQ ID NO:1 or SEQ ID NO:3, wherein the receptor polypeptide binds GLP-1 with a Kd of less than 100 nM.

REFERENCES:
patent: 5670360 (1997-09-01), Thorens
Richter, G., et al. (1990) Febs Lett. 267:78-80.
Richter, G., et al. (1991) Febs Lett. 280:247-50.
Uttenthal, L. O., et al. (1990) Febs Lett. 262:139-41.

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