Receptor for oncostatin M

Details Receptor for oncostatin M Receptor for oncostatin M

1998-04-10

1999-04-06

Caputa, Anthony

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530395, 530402, C07K 14715

Patent

active

058919970

ABSTRACT:
A novel polypeptide functions as the .beta. chain of an oncostatin M receptor and is thus designated OSM-R.beta.. Heterodimeric receptor proteins comprising OSM-R.beta. and gp130 bind oncostatin M and find use in inhibiting biological activities mediated by oncostatin M.

REFERENCES:
patent: 5284744 (1994-02-01), Gearing et al.
Rudinger, In Peptide Hormones, ed. J.A. Parsons, University Park Press, Baltimore, pp. 1-6, 1976.

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