Receptor for biochemical assay system

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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232303, 23230B, 23920, 424 15, G01N 3316, A61K 4300

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active

042028752

ABSTRACT:
Components for a biochemical assay system for diagnosis of myasthenia gravis in humans. Acetylcholine receptor protein is extracted from non-human mammalian fetal muscle tissue. The acetylcholine receptor protein is then used in a bio-assay system as a complex of the acetylcholine receptor protein and a toxin labeled with a radioactive isotope.

REFERENCES:
patent: 4033722 (1977-07-01), Lindstrom
Fambrough et al., "Neuromuscular Junction in Myasthenia Gravis Decreased Acetylcholine Receptors", Science, vol. 182, Oct. 1973, pp. 293-295.
Almon et al., "Serum Globulin in Myasthenia Gravis: Inhibition of Bungarotoxin to Acetylcholine Receptors", Science, vol. 186, No. 4158, Oct. 1974, pp. 55-57.

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