Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Reexamination Certificate
2005-01-10
2009-02-17
Campell, Bruce (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
C424S184100, C424S185100, C424S192100, C424S202100, C530S300000, C530S350000
Reexamination Certificate
active
07491397
ABSTRACT:
Isolated polypeptides containing fragments of SARS CoV S protein and functional equivalents thereof. Also disclosed are isolated nucleic acids encoding the polypeptides, related expression vectors, related host cells, related antibodies, and related compositions. Methods of producing the polypeptide, diagnosing infection with a coronavirus, and identifying a test compound for treating infection with a coronavirus are also disclosed.
REFERENCES:
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Shortridge. SARS exposed, pandemic influenza lurks. The Lancet, May 10, 2003, vol. 361, p. 1649.
Godeke et al., “Assembly of Spikes into Coronavirus Particles is Mediated by the Carboxy-Terminal Domain of the Spike Protein,” Journal of Virology, 74(3):1566-1571 (2000).
Kuo et al., “Retargeting of Coronavirus by Substitution of the Spike Glycoprotein Ectodomain: Crossing the Host Cell Species Barrier,” Journal of Virology, 74(3):1393-1406 (2000).
Chong Pele Choi Sing
Hsieh Shie-Liang
Campell Bruce
Humphrey Louise
National Health Research Institutes
Occhiuti Rohlicek & Tsao LLP
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