Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Reexamination Certificate
2011-04-19
2011-04-19
Saoud, Christine J (Department: 1646)
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
C424S185100, C514S021200
Reexamination Certificate
active
07927583
ABSTRACT:
The present invention provides a fusion polypeptide capable of binding a cytokine to form a nonfunctional complex. It also provides a nucleic acid sequence encoding the fusion polypeptide and methods of making and uses for the fusion polypeptide.
REFERENCES:
patent: 5470952 (1995-11-01), Stahl et al.
patent: 5844099 (1998-12-01), Stahl et al.
patent: 5945511 (1999-08-01), Lok et al.
patent: 6472179 (2002-10-01), Stahl et al.
patent: 6610750 (2003-08-01), Charbit et al.
patent: 0835939 (1991-06-01), None
patent: 0533006 (1992-09-01), None
patent: WO 93/19163 (1993-09-01), None
patent: WO 93/19777 (1993-10-01), None
patent: WO 94/22914 (1994-10-01), None
patent: WO 95/06737 (1995-03-01), None
patent: WO 96/11213 (1996-04-01), None
patent: WO9611213 (1996-04-01), None
patent: WO 96/23881 (1996-08-01), None
patent: WO 96/35783 (1996-11-01), None
patent: WO 97/15669 (1997-05-01), None
patent: WO 97/31946 (1997-09-01), None
patent: WO 99/37772 (1999-07-01), None
Greenfeeder, SA et al. 1995. Molecular Cloning and Characterization of a Second Subunit of the Interleukin-1 Receptor Complex. J Bio Chem 270(23):13757-13765.
Seipelt, I et al. 1997. Overexpression, Purification, and Use of a Soluble Human Interleukin-4 Receptor alpha chain/IgG1 Fusion Protein for Ligand Binding Studies. BioChem & BioPhys Res Comm 239:534-542.
Stahl, N et al. 1999. Cytokine Traps: Heteromeric Receptor-Based Protein Therapeutics that Function as High-Affinity Blockers of Cytokine Action. FASEB Journal Abstract 1457.
Stahl Neil
Yancopoulos George D.
Cottingham Frank R.
Gregg Valeta
Regeneron Pharmaceuticals Inc.
Saoud Christine J
Seharaseyon Jegatheesan
LandOfFree
Receptor based antagonists and methods of making and using does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Receptor based antagonists and methods of making and using, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Receptor based antagonists and methods of making and using will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2633968