Rebeccamycin and process for its preparation

Details Rebeccamycin and process for its preparation Rebeccamycin and process for its preparation

1983-01-28

1984-12-11

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, C07H 1700

Patent

active

044879253

ABSTRACT:
A novel antitumor agent designated herein as rebeccamycin is produced by fermentation of Nocardia aerocolonigenes (ATCC 39243). Rebeccamycin and its 5'-N-methyl and 5',2",3",6"-tetraacetate derivatives exhibit activity against experimental animal tumor systems.

REFERENCES:
Furwaki et al., Journ. Chem. Comm. (J.C.S.), 1978, pp. 800-801.
Omura et al., Journ. Antibiotics 30 (4); 275-282 (1977).
Steglich et al., Angew. Chemie 19 (6), pp. 459-460 (1980).

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