Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1976-05-19
1977-05-31
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 87, A61K 3902, A61K 3940
Patent
active
040270114
ABSTRACT:
To improve the resistance of pigs to gastro-intestinal disorders, the endotoxins of one or more of the pathogenic E. coli serotypes C8, 045, 0138, 0139, 0141, 0147 and 0149 are introduced into the pig intestine. Administration, which may for example be in water or in a pig feed, stimulates the pig intestine to produce antibodies to the E. coli organisms.
REFERENCES:
Vet. Bull. 38, No. 3912, No. 3416, No. 2959 (1968), 39, No. 2775, No. 3195, No. 935-936 (1969), 40, No. 3762-3765 (1970), 41, No. 3197, No. 3205 (1971).
Sojka, July, 1971, Vet. Bull. 41(7), 509-522, "Enteric Diseases in New-Born Piglets, Calves, and Lambs Due to Escherichia coli Infection".
Kohler, Dec., 1968, Am. J. Vet. Res., 29(12), 2263-2274, "Enterotoxic Activity of Filtrates of Eschorichia coli in Young Pigs".
Kohler, Kohler et al., May, 1971, Am. J. Vet. Res., 32(5), 731-737, 738-748, "Enterotoxic Activity of Whole Cell Lysates of Escherichia coli in Young Pigs; Feeding Bacteria-Free Whole Cell Lysates of Escherichia coli to Gnotobiotic Pigs".
Hill Ian Roland
Kenworthy Raymond
Porter Philip
Kramer Barry
N.V. Internationale Octrooi Maatschappij "Octropa"
Rose Shep K.
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