Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...
Patent
1995-06-19
1997-04-29
Gorgos, Kathryn L.
Chemistry: electrical and wave energy
Processes and products
Electrophoresis or electro-osmosis processes and electrolyte...
204454, 204600, 204601, G01N 2726
Patent
active
056245394
ABSTRACT:
An electrophoretic separation apparatus includes a capillary tube having a length, a cross section, an inlet and an outlet. A first reservoir containing a solvent and, upon injection, a solute is in fluid-flow communication with the inlet and a second reservoir containing at least a solvent is also in fluid flow communication with the outlet, the capillary thereby being filled at least with the solvent. A first power supply applies a direct voltage separation potential between the first and second reservoirs and along the length of the capillary to thereby establish an electrophoretic flow of the solute therethrough. A second power supply applies an alternating voltage upon the direct voltage, and the DC impedance and AC impedance values are determined and subtracted to provide a direct measurement of the electroosmotic flow.
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E. Delatour, et al. Apparatus for Alternating Field Microelectrophoresis, Rev. Sci. Instrum., vol. 47, No. 12, Dec. 1976, 1531-1535.
Ewing Andrew G.
Hayes Mark A.
Gorgos Kathryn L.
Monahan Thomas J.
Noguerola Alex
The Penn State Research Foundation
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