Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving glucose or galactose
Patent
1994-10-24
1997-09-16
Kight, John
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving glucose or galactose
435 4, 435 25, 435 15, 435817, C12Q 154, C12Q 100, C12Q 126, C12Q 148
Patent
active
056679831
ABSTRACT:
It has been found that imidazole and related buffers enhance the activity of certain preservatives, for example either (1) a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one or (2) 5-bromo-5-nitro-1,3-dioxane, that are used in clinical diagnostic reagents. It has also been found that these buffers and certain surfactants, such as BRIJ 700 and related hydrophilic surfactants, enhance the precision and accuracy of enzyme biosensors.
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Abel Allison L.
D'Orazio Paul A.
Dalzell Bonnie C.
McCaffrey Robert R.
Uretsky Laura S.
Blackburn Robert P.
Chiron Diagnostics Corporation
Kight John
Leary Louise
Morgenstern Arthur S.
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