Reagents for detection of primary amines

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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544333, 536 187, 536 271, 530324, 530326, 530327, 530330, 436111, 436 86, 436 89, 436128, 436149, 436150, 436161, C07D47108, C07K 504, C07K 704, C08B 3700, C07H 1702

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056313748

ABSTRACT:
The present invention is directed to derivatives of aroyl-2-quinoline-carboxaldehyde and their use in detection and quantification of minute amounts of primary amines.

REFERENCES:
patent: 4723022 (1988-02-01), Givens et al.
patent: 4837166 (1989-06-01), de Montigny et al.
patent: 4910314 (1990-03-01), de Montigny et al.
Beale et al. (1988) Fluorescence Reagents for High-Sensitivity Chromatographic Measurements of Primary Amines. Anal. Chem. 60: 1765-1769.
Beale et al. (1989) 3-Benzoyl-2-Quinolineacarboxaldehyde: A Novel Fluorogenic Reagent for the High-Sensitivity Chromatographic Analysis for Primary Amines. Talanta 36:321-325.
Beale et al. (1990) Application of 3-(2-Furoyl)Quinoline-2-Carbaldehyde as a Fluorogenic Reagents for the Analysis of Primary Amines by Liquid Chromatograpy with Laser-Induced Fluorescence Detection. J. Chromatography 499:579-587.
de Montigny et al. (1987) Naphthalene-2,3-dicarboxaldehyde/Cyanide Ion: A Rationally Designed Fluorogenic Reagent for Primary Amines., Anal. Chem. 59:1096-1101.
Gluckman, et al. (1984) Laser Fluorimetry for Capillary Column Liquid Chromatography: High-Sensitivity Detection of Derivatized Biological Compounds. Journal of Chromatography 317:443-453.

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