Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Albumin
Patent
1989-04-10
1992-03-31
Lacey, David L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Albumin
25230116, 25230118, 436501, 436 56, 436901, G01N 33536, C09K 1106
Patent
active
051010151
ABSTRACT:
A fluorescence polarization immunoassay (FPIA) for detecting the presence of one or more amphetamine-class analytes in a test sample is provided. The immunoassay uses competition between the analyte and a fluorescently labeled tracer for the binding site on an antibody specific for phenethylamine derivatives. The concentration of amphetamine-class analyte in the sample determines the amount of tracer that binds to the antibody. The amount of tracer/antibody complex formed can be quantitatively measured and is inversely proportional to the quantity of analyte in the test sample. The invention relates to tracers, to immunogens used to elicit antibodies for use as assay reagents, and to assay kits incorporating these tracers and assay reagents.
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Brynes Paul J.
Flentge Charles A.
Johnson Donald D.
Jonas Patrick F.
Molina Cynthia M.
Abbott Laboratories
Breininger Thomas M.
Daley Thomas E.
Hastreiter Roberta L.
Lacey David L.
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