Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-11-05
1999-08-17
Degren, Nancy
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4351723, 4353201, 435325, 536 231, 536 235, C12Q 168, C12N 1500, C12N 1563, C12N 1585
Patent
active
059392657
ABSTRACT:
A set of contiguous and partially overlapping RNA sequences and polypeptides encoded thereby, designated as LU103 and transcribed from lung tissue is described. A fully sequenced clone representing the longest continuous sequence of LU103 is also disclosed. These sequences are useful for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the lung such as lung cancer.
REFERENCES:
patent: 5019497 (1991-05-01), Olsson
Sudo et al., GenBank. Accession # D31079, Feb. 1995.
Hiller et al., GenBank. Accession # N92483, Apr. 1996.
Database Embl; AC: W40141; ID: HS141342, Fetal lung NbH119W Homo sapiens cDNA clone, May 21, 1996; Hillier et al.: "The WashU-Merck EST Project"; XP002059613.
Database; Embl: AC:W17168; ID: HS168332: Fetal lung NbH119W Homo sapiens cDNA clone, May 4, 1996; Hiller et al.: "The WashU-Merck EST Project"; XP002059614.
Database; Embl; AC:D30961; ID: HSL11877, Feb. 9, 1995; Sudo et al.: "2058 expressed ESTs from a human fetal lung cDNA library"; XP002059615.
Schwartz, M. K.; "Current status of Tumour Markers"; Scandinavian Journal of Clinical & Laboratory Investigation, vol. 55, No. Suppl. 221, Jan. 1,1995, pp. 5-14, XP000490502.
Bennett, William P., "p53 Alterations in Progenitor Lesions of the Bronchus, Esophagus, Oral Cavity, and Colon," Cancer Detection and Prevention 19(6):503-511 (1995).
Chen et al., "Isolation and Characterization of a Novel Gene Expressed in Multiple Cancers," Oncogene 12:741-751 (1996).
Endler et al. "Two-Dimensional Electrophoresis of Proteins in Tumors of the Lung," J. Clin. Chem. Clin. Biochem. 24:981-992 (1986).
Ginsberg et al., "Cancer of the Lung" Cancer Principles and Practice of Oncology, Fourth Edition V. T. DeVita Jr., S. Hellman, S. A. Rosenburg,673-723 Philadelphia, PA: J. B. Lippincott Co. (1993).
Hirano et al., "Detection of Polypeptides Associated wit the Histopathological Differentiation of Primary Lung Carcinoma," British Journal of Cancer 72:840-848 (1995).
Jacobs et al., "Clinical Use of Tunor Markers In Oncology," Curr Probl. Cancer 15:299-349 (1991).
Liang et al., "Differential Display and Cloning of Messenger RNAs From Human Breast Cancer versus Mammary Epithelial Cells," Cancer Research 52:6966-6968 (1992).
Schwartz, M.K., "Cancer Markers," Cancer: Principles and Practice of Oncology pp. 531-542.
Steeg et al., "Evidence for a Novel Gene Associated With Low Tumor Metastatic Potential," Journal of the National Cancer Institute 80(3):200-204 (1988).
Cohen Maurice
Friedman Paula N.
Gordon Julian
Hodges Steven C.
Klass Michael R.
Abbott Laboratories
Becker Cheryl L.
Degren Nancy
Goller Mimi C.
Wang Andrew
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