Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Reexamination Certificate
2007-10-16
2007-10-16
Harris, Alana M. (Department: 1642)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
C424S184100, C424S192100, C424S193100, C435S007100, C530S300000, C530S350000, C530S388100, C530S388150, C530S389100, C530S387100, C530S387700, C530S387900
Reexamination Certificate
active
09549342
ABSTRACT:
This invention relates generally to a multimeric polypeptide complex/antigen which may be utilized in detecting or diagnosing diseases of the uterus such as uterine cancer. Furthermore, the invention relates to methods and kits, for example, which utilize this antigen or an antibody thereto. The complex itself comprises at least one EU250 polypeptide and at least one polypeptide which may be a BU101 polypeptide and/or a TU104 polypeptide. The complex may further comprise other, as yet unknown, polypeptide sequences.
REFERENCES:
patent: 5668267 (1997-09-01), Watson et al.
patent: 6066724 (2000-05-01), Ni et al.
patent: 6379671 (2002-04-01), Colpitts
patent: 9734997 (1997-09-01), None
patent: 9807857 (1998-02-01), None
patent: 9821331 (1998-05-01), None
patent: 0035950 (2000-06-01), None
Amino acid database, Seq ID# 2,4 & 6 of U.S. Patent No. 6, 066, 724, 2000.
T. E. Creighton et al., In: Proteins: Structures and Molecular Properties, Second Edition, pp. 78-102, New York, NY: W. H. Freeman and Co. 1993.
Friedman, P. et al. “BU101: A new breast specific uteroglobin.” Anti Cancer Research, (Sep.-Oct., 1998) vol. 18 No. 5C, pp. 3840-3841—Meeting Info.: 22ndInternational Breast Cancer Research Congress Of The International Association For Breast Cancer Research Athens, Greece Sep. 24-27, 1998: XP000929344.
Watson M. A. et al. “Mammaglobin, A Mammary-Specific Member of the Uteroglobin Gene Family, Is overexpressed in Human Breast Cancer”—Cancer Researdch, US, American Association for Cancer Research, Baltimore, MD, vol. 56, Feb. 15, 1996 pp. 860-865: XP002048615.
Colpitts Tracey L.
Russell John C.
Abbott Laboratories
Becker Cheryl L.
Harris Alana M.
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