Reagents and methods for the detection and quantification of thy

Details Reagents and methods for the detection and quantification of thy Reagents and methods for the detection and quantification of thy

1994-07-13

1997-01-14

Ceperley, Mary E.

Chemistry: analytical and immunological testing

Thyroid hormone tests

43524027, 436546, 436817, 53038824, 5303892, 530807, G01N 3378, G01N 33533, C07K 1626

Patent

active

055938965

ABSTRACT:
Immunoassay methods and reagents for the specific quantification of thyroxine in a test sample are disclosed employing antibodies prepared with thyroxine derivatives of the formula: ##STR1## wherein P is an immunogenic carrier material and X is a linking moiety. The present invention also describes the synthesis of unique labelled reagent of the formula: ##STR2## wherein Q is a detectable moiety and W is a linking moiety, preferably fluorescein or a fluorescein derivative.

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