Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Chemical aftertreatment – e.g. – acylation – methylation – etc.
Patent
1995-04-28
1996-09-24
Kight, John
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Chemical aftertreatment, e.g., acylation, methylation, etc.
530399, 530812, 536 2351, 536 221, 536 187, 435 52, 435 25, 435 26, 435 28, 4241451, 4241581, A61K 3800, A61K 3824, C07H 2104, C12Q 126
Patent
active
055592104
ABSTRACT:
A Position 1 immunogen having the following formula: ##STR1## wherein: (a) P represents an immunogenic carrier material
REFERENCES:
patent: 4031117 (1977-06-01), Rao
patent: 4085202 (1978-04-01), Rao
patent: 4150105 (1979-04-01), Gross
patent: 4197286 (1980-04-01), Rao
patent: 4279992 (1981-07-01), Boguslaski et al.
patent: 4342739 (1982-08-01), Kakimi et al.
patent: 4474893 (1984-10-01), Reading
patent: 4510251 (1985-04-01), Kirkemo et al.
patent: 4676980 (1987-06-01), Segal et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4975420 (1990-12-01), Silversides et al.
patent: 5002883 (1991-03-01), Bieniarz et al.
patent: 5180828 (1993-01-01), Ghazarossian et al.
W. Eechaute et al., "The Conversion of Testosterone to 7.sup..alpha. -Hydroxy-Testosterone by Incubated Rat Testes", Steroids, vol. 24:6, Dec. 1974, pp. 753-759.
R. Condom et al., "Preparation of Steroid-Antigens through Positions of the Steroid not Bearing Functional Groups", Steroids, vol. 23:4, Apr. 1974, pp. 483-498.
M. Kocor et al., "Steroids. Part XLI.sup.*. Michael Addition of Diethyl Malonate to Steroidal 3-keto-1,4,6-Trienes", Polish Journal of Chemistry, vol. 53, 149, 1979, pp. 149-155.
J. F. Sabot et al., "Determination of Plasma Testosterone by Mass Fragmentography using (3,4-.sup.13 C) Testosterone as an Internal Standard", Journal of Chromatography, vol. 339 (1985) pp. 233-242.
Y. Shinohara et al., "Pharmacokinetic Studies of Testosterone Propionate Using Gas Chromatography/Mass Spectrometry/Selected Ion Monitoring", Biomedical and Environmental Mass Spectrometry, vol. 16 (1988) pp. 241-244.
T. Furuta et al., "Simultaneous Measurements of Endogenous and Deuterium-labelled Tracer Variants of Androstenedione and Testosterone by Capillary Gas Chromatography Mass Spectrometry", Journal of Chromatography, vol. 525 (1990) pp. 15-53.
S. Fukushima et al., "Simultaneous determination of Testosterone and Androstadienone (sex attractant) in human plasma by gas chromatography-mass spectrometry with high-resolution selected-ion monitoring", Journal of Chromatography, vol. 565 (1991) pp. 35-44.
S. A. Wudy et al., "Androgen metabolism assessment by routine gas chromatography/mass spectrometry profiling of plasma steroids: part 1, unconjugated steroids", Steroids, vol. 57 (1992), pp. 319-324.
L. Siekmann, "Determination of Steroid Hormones by the Use of Isotope Dilution-Mass Spectrometry: A Definitive Method in Clinical Chemistry", Journal of steroid Biochemistry, vol. 11 (1979), pp. 117-123.
G. Moneti et al., "Determination of Testosterone and its tissue metabolites (DHT and 3.alpha.-DIOL) in Human Plasma and Prostatic tissue by Isoptopic Dilution Mass Spectrometry", Journal of Steroid Biochem, vol. 27 (1897), pp. 53-59,.
P. Vingler et al., "Direct quantitative digital autoradiography-thin-layer chromatography of 3.alpha.,3.beta. -and 5.alpha.-reduced and 17.beta.dehydrogenated androgens derived from testosterone metabolism", Journal of Chromatography, vol. 571 (1991) pp. 73-86.
A. Syropoulos et al., "Flow-injection chemiluminometric analysis of some steroids by their sensitizing effect on the bromate-sulphite reaction", Analytica Chimica Acta, vol. 239 (1990), pp. 195-202.
T. V. Stabler et al., "Chemiluminescene Immunoassay of Aldosterone in Serum", Clinical Chemistry, vol. 37 (1991), pp. 1988-1989.
Y. Suzuki et al., "Automated Direct Assay System for the Measurement of Sex Steroid Hormones in Serum using High-Performance Liquid Chromatography", Journal of Chromatography, vol. 426(1988), pp. 33-40.
F. U. Eroc et al., "High-Performance Liquid Chromatographic Analysis of Steroid Hormones", Journal of Chromatographic Science, vol. 27 (1989), pp. 86-90.
H. Ueshiba et al., "Serum Profiles of Steroid Hormones in Patients with Cushing's Syndrome Determined by a New HPLC/RIA Method", Clinical Chemistry, vol. 37(1991), pp. 1329-1333.
H. Hosoda et al., "Sensitivity and Specificity in Enzyme Immunoassay of Testosterone", Chemical Pharm. Bull., vol. 28(1980), pp. 3035-3040.
G. J. Marcus et al., "A Simple Enzyme-linked Immunosorbent Assay for Testosterone" Steroids, vol. 46(1985), pp. 975-986.
E. Ali et al., "Sandwich immunoassay of small molecules I. Investigation with testosterone as model hapten", Journal of Immunological Methods, vol. 147(1992), pp. 173-179.
J. Sengupta et al., "Sandwich immunoassay of small molecules, II. Effects of heterology and development of a highly sensitive and specific enzyme immunoassay for testosterone", Journal of Immunological Methods, vol. 147(1992), pp. 181-188.
T. K. Dhar et al., "Direct microtitre plate enzyme immunoassay of testosterone in unextracted serum", Journal of Immunological Methods, vol. 147(1992), pp. 167-172.
M. J. Rassaie et al., "A highly specific heterologous enzyme-linked immunosorbent assay for measuring testosterone in plasma using antibody-coated immunoassay plates or polypropylene tubes", Steroids, vol. 57(1992), pp. 288-294.
M. J. Rassaie et al., "Influence of different combinations of antibodies and penicillinase-labeled testosterone derivatives on sensitivity and specificity of immunoassays", Steroids, vol. 57(1992), pp. 112-118.
P. N. Rao et al., "Synthesis of New Steroid Haptens for Radioimmunoassay-Part V. 19-.omicron.-Carboxymethyl Ether Derivative of Testosterone. A Highly Specific Antiserum for Immunoassay of Testosterone from both Male and Female Plasma without Chromatography", Journal of Steroid Biochemistry, vol. 9(1978), pp. 539-545.
H. Hosoda et al., "Preparation and Antigenic Properties of Testosterone-4-Bovine serum Albumin Conjugates", Journal of Steroid Biochemistry, vol. 10 (1979), pp. 513-517.
S. Z. Cekan, "On the Assessment of Validity of Steroid Radioimmunoassays", Journal of Steroid Biochemistry, vol. 11(1979), pp. 1629-1634.
T. W. Greene et al., Protective Groups in Organic Synthesis, 2nd Ed., John Wiley & Sons, Inc., New York, 1991.
G. Kohler et al., "Striated muscle fibres differentiate in monolayer cultures of adult thymus reticulum", Nature, vol. 256 (1975), pp. 493-497.
Adamczyk Maciej
Artip Sharon G.
Chen Yon-Yih
James Bryan D.
Walling John A.
Abbott Laboratories
Kight John
Leary Louise N.
Weinstein David L.
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