Reagents and methods for preparing LPS antagonist B1287 and...

Details Reagents and methods for preparing LPS antagonist B1287 and... Reagents and methods for preparing LPS antagonist B1287 and...

2011-03-15

2011-03-15

Olson, Eric S (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C514S025000, C514S062000, C536S004100, C536S018400, C536S055200

Reexamination Certificate

active

07906633

ABSTRACT:
The present invention provides methods for preparing LPS antagonist lipodisaccharide B1287 and stereoisomers thereof, which compounds are useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock. Also provided are synthetic intermediates useful for implementing the inventive methods.

REFERENCES:
patent: 6184366 (2001-02-01), Christ et al.
patent: 6809195 (2004-10-01), Sanghvi et al.
patent: WO 96/39411 (1996-12-01), None
Protective groups in Organic synthesis, by Greene and Wuts, published 1999 by John Wiley and Sons, pp. 183-185.

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