Reagents and method for therapeutic treatment of multiple sclero

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31415

Patent

active

051029022

ABSTRACT:
The administration internally to humans of certain imidazol derivatives, especially N"-cyano-N-methyl-N'-[2[[(5-methyl-1H-imidazol-4-yl) methyl]thio]-ethyl]-guanidine (cimetidine) or salts thereof, is an effective therapeutic treatment for multiple sclerosis, both acute and chronic. The imidazole moiety is theorized to directly inhibit spread of the virus theorized to cause multiple sclerosis. Treatment of multiple sclerosis with metronidazole with one bolus dose on a frequency of once a day or less and with cimetidine on a frequency of twice per day has been found to be highly efficatious with minimal suppression of the patient's natural immune system and minimal long term peripheral nerve damage.

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