Reagent test strip for blood glucose determination

Details Reagent test strip for blood glucose determination Reagent test strip for blood glucose determination

1996-04-04

1998-05-19

Leary, Louise

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving glucose or galactose

435 4, 4352871, 435970, 435808, 422 50, 422 55, 422 681, C12Q 154, C12Q 100, G01N 3353, G01N 2100

Patent

active

057534527

ABSTRACT:
A reagent test strip is adapted for use in a blood glucose meter. A sample of whole blood is applied to one surface of a matrix on the strip and the meter measures the reflectance of the opposite surface of the matrix at about 635 nm and 700 nm and calculates from the reflectances the concentration of glucose in the sample. The portion of the applied sample that penetrates the matrix and is visible from the testing surface does not absorb to any appreciable extent at 700 nm. Nevertheless, the glucose-containing sample interacts with the components of the reagent-containing matrix to cause a change in reflectance at 700 nm that simulates the effect of the blood color. As a result, the strip can be used in meters that measure glucose concentration in whole blood samples in the presence of optically visible hemoglobin.

REFERENCES:
patent: 4935346 (1990-06-01), Phillips et al.
patent: 5304468 (1994-04-01), Phillips et al.
patent: 5306623 (1994-04-01), Kiser et al.
patent: 5453360 (1995-09-01), Yu
Capaldi, Dante J. and Taylor, Keith E. Analytical Biochemistry 129, 329-336 (1983) "A new Peroxidase Color Reaction: Oxidative Coupling of 3-Methyl-2-Benzothiazolinone Hydrazone (MBTH) with its Formaldehyde Azine. Application to Glucose and Choline Oxidases" month not available.

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