Reagent sheet and integral multilayer analytical element for mea

Details Reagent sheet and integral multilayer analytical element for mea Reagent sheet and integral multilayer analytical element for mea

1986-06-20

1990-04-10

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving transferase

435288, C12Q 148

Patent

active

049160591

ABSTRACT:
A reagent sheet for the measurement of GGT (.gamma.-glutamyl transferase) activity comprising a porous sheet containing a cationic surfactant and a self-developable substrate upon contact with .gamma.-glutamyl transferase. An integral multilayer analytical element for the measurement of GGT activity, comprising a porous spreading layer containing a cationic surfactant and a self-developable substrate in response to contact with .gamma.-glutamyl transferase, a water-absorbing layer and a support in a laminated form. The substrate can be either .gamma.-glutamyl-p-nitroamilide or .gamma.-glutamyl-3-carboxy-4-nitroamilide.

REFERENCES:
patent: 3891507 (1975-06-01), Breuer
patent: 4087331 (1978-05-01), Bucolo et al.
patent: 4372874 (1983-02-01), Modrovich
patent: 4603107 (1986-07-01), Deneke et al.
Konishiroku-Chem. Abst., vol. 100 (1984) p. 47792h.

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