Reagent for the precipitation of apo-B-containing lipoproteins

Details Reagent for the precipitation of apo-B-containing lipoproteins Reagent for the precipitation of apo-B-containing lipoproteins

1982-04-19

1985-06-04

Padgett, Ben R.

Chemistry: analytical and immunological testing

Composition for standardization, calibration, simulation,...

Preparation composition

436174, 436825, G02N 3348

Patent

active

045215197

ABSTRACT:
The present invention provides a reagent for the precipitation of apo-B-containing lipoproteins, wherein it comprises 0.2 to 3 grams per liter of phosphotungstic acid and more than 2 mmols per liter of magnesium ions in aqueous solution.
The present invention also provides a process for the preparation of this reagent and a process for the precipitation of apo-B-containing lipoproteins using this reagent.

REFERENCES:
patent: 3873433 (1975-03-01), Seidel et al.
patent: 4210557 (1980-07-01), Handschuh
patent: 4226713 (1980-10-01), Goldberg
Burstein, M. et al., Life Sciences, vol. 8(8), pp. 345-348, (1969).
Lopes-Virella, M. et al., Clin. Chem., vol. 23(5), pp. 882-884, (1977).
Warnick, G. R. et al., Clin. Chem., vol. 25(4), pp. 596-604, (1979).
Pinkowitz, R. A. et al., Clin. Chem., vol. 25(6), p. 1146, Abstract 416 (1979).
Hohenwaller, W. et al., Clin. Chem., vol. 26(1), pp. 177-178, (1980).
Draeger, B. et al., Lipopr. Coron. Heart Dis. Int. Symp., pp. 38-42, (1979).
Sale et al., Clinica Chimica Acta, vol. 112, pp. 375-377, (1981).
Warnick, G. R. et al., Am. J. Clin. Path., vol. 78(5), pp. 718-723, (1982).
Burstein, M. et al., Journal of Lipid Research, vol. 11, pp. 583-595, (1970).
Clin. Chem. 25 (1979), pp. 939-942, Kosner, G. M. et al.,
Draeger et al., Lipoproteine und Herzinfarkt.

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