Reagent for fluorimetric determination of analytes

Details Reagent for fluorimetric determination of analytes Reagent for fluorimetric determination of analytes

2008-04-22

2010-10-05

Gitomer, Ralph (Department: 1657)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving oxidoreductase

C436S172000, C436S800000, C436S904000

Reexamination Certificate

active

07807402

ABSTRACT:
A method and reagent for detecting the presence or amount of an analyte by a redox reaction and a fluorimetric determination, is disclosed. The reagent comprises a compound of the general formula Q-F as a redox indicator, wherein Q is a quencher group and F is a fluorophore group. The quencher group Q or/and the fluorophore group F can be reduced or oxidized, and the fluorescence can change depending on the reduction or oxidation.

REFERENCES:
patent: 4558130 (1985-12-01), Buckler et al.
patent: 4656141 (1987-04-01), Birks et al.
patent: 5445944 (1995-08-01), Ullman
patent: 5795729 (1998-08-01), Lee
patent: 5912139 (1999-06-01), Iwata et al.
patent: 6468753 (2002-10-01), Smith et al.
patent: 7332354 (2008-02-01), Heindl et al.
patent: 7378255 (2008-05-01), Horn et al.
patent: 2003/0186349 (2003-10-01), Makings
patent: 0 190 740 (1986-08-01), None
patent: 0 431 456 (1990-11-01), None
patent: 0 441 222 (1991-08-01), None
patent: 0 620 283 (1994-03-01), None
patent: 0 574 769 (1996-04-01), None
patent: 0 831 327 (1997-09-01), None
patent: 63277680 (1988-11-01), None
patent: WO 91/09139 (1991-06-01), None
patent: WO 93/06487 (1993-04-01), None
Song et al. Photophysical Properties of Polyads Containing a Fluorescein Moiety. Dyes and Pigments 42 (1999) 149-158.
Zhang et al. Photoinduced Intramolecular Electron Transfer in an Anthraquinone-Fluorescein-Carbazole Model. J of Phtochemistry and Photobiology A Chemistry 103 (1997) 63-67.
Haugland, R P, Chapter 10—Section 10.5: Substrates for Miscellaneous Enzymes, Handbook of Fluorescent Probes and Research Chemicals, 1996, 6th ed., Molecular Probes, pp. 236-237, Eugene, OR, USA.
Ryabov, A D, Firsova, Y N, Ershov, A Y, Dementiev, I A. Spectrophotometric kinetic study and analytical implications of the glucose oxidase-catalyzed reduction of [Miii(LL)2Cl2]+complexes by D-glocuse (M= Os and Ru, LL=2,2′—bipyridine and 1,10-phenanthroline type ligands), JBIC 1999, 4:175-182.
Woltman, S J, Even, W R, Weber, S G. “Chromatographic Detection Using Tris (2,2′—bipyridyl)ruthenium (III) as a Fluorogenic Electron- Transfer Reagent”, Anal. Chem. 1999, 71, 1504-1512.
Haugland, R P, “Handbook of Fluorescent Probes and Research Chemicals”, Molecular Probes, Sixth Edition, Chapter.10 —Section 10.5 Substrates for Miscellaneous Enzymes, pp. 236-237.
Borchardt, R T, Cohen, L A, “Stereopopulation Control. III. Facilitation of Intramolecular Conjugate Addition of the Carboxyl Group”, Journal of the American Chemical Society, 94:26, Dec. 27, 1972, 9175-9182.
Song. A, Zhang, H, Zhang. M, Shen, T. “Photophysical properties of polyads containing a fluorescein moiety”, Dyes and Pigments 42 (1999) 149-158.
Zhang, H, Zhang, M, Shen, T. “Photoinduced intramolecular electron transfer in an anthraquinone-fluorescein-carbazole model”, Journal of Photochemistry and Photobiology A: Chemistry 103 (1997) 63-67.
Lakowicz, J.R., Chapters 13, 14 & 15, Principles of Fluorescence Spectroscopy, Kluwer Academic/Plenum Publishers, New York, NY 1999, pp. 367-443.

Affiliated with

Also associated with

Rating

Reagent for fluorimetric determination of analytes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Reagent for fluorimetric determination of analytes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reagent for fluorimetric determination of analytes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4238976