Reagent for endotoxin-specific assay

Details Reagent for endotoxin-specific assay Reagent for endotoxin-specific assay

1994-09-28

1997-12-30

Hollinden, Gary E.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 18, 435 13, 435 23, 435184, 435975, 435 14, 436 74, 436 69, 436 63, C12Q 100, C12Q 134, C12Q 156, G01N 3353

Patent

active

057028826

ABSTRACT:
Endotoxin (Et) can be specifically assayed by exclusively utilizing the factor C system reaction without being affected by factor G contained in a limulus amebocyte lysate reagent.
The present invention provides: (1) a reagent for ET-specific assay which comprises a limulus amebocyte lysate reagent and an alkylglucoside; (2) a method of specifically assaying Et in a specimen using a limulus amebocyte lysate reagent, wherein an alkylglucoside is added to the limulus amebocyte lysate reagent and/or the specimen; and (3) a factor G activation inhibitor composition which comprises an alkylglucoside as an active ingredient capable of inhibiting the activation of factor G in limulus amebocyte by (1.fwdarw.3)-.beta.-D-glucan.

REFERENCES:
patent: 4322217 (1982-03-01), Dikeman
patent: 5047353 (1991-09-01), Tsuchiya et al.
patent: 5155032 (1992-10-01), Tanaka et al.
patent: 5179006 (1993-01-01), Matuura et la.
patent: 5286625 (1994-02-01), Tanaka et al.
patent: 5378610 (1995-01-01), Tanaka et al.
patent: 5389547 (1995-02-01), Tanaka et al.
patent: 5401647 (1995-03-01), Tanaka et al.

Affiliated with

Also associated with

Rating

Reagent for endotoxin-specific assay does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Reagent for endotoxin-specific assay, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reagent for endotoxin-specific assay will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-201202