Reagent for determining (1.fwdarw.3)-.beta.-D-glucan

Details Reagent for determining (1.fwdarw.3)-.beta.-D-glucan Reagent for determining (1.fwdarw.3)-.beta.-D-glucan

1995-02-21

1997-10-28

Kight, John

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving blood clotting factor

435 4, 435 18, 435 19, 435 23, 435 24, 435 34, 436 63, 436 74, C12Q 156, C12Q 100, C12Q 134, C12Q 144

Patent

active

056817100

ABSTRACT:
The present invention provides a reagent for determining (1.fwdarw.3)-.beta.-D-glucan comprising a lysate substantially free from any endotoxin-sensitive factor, which is obtained by contacting limulus amebocyte lysate optionally containing dextran with a polyamide or cellulose insoluble carrier, which makes it possible to rapidly and easily determine at a high accuracy (1.fwdarw.3)-.beta.-D-glucan of mycotic origin contained in the body fluid such as blood or urine.

REFERENCES:
patent: 4606824 (1986-08-01), Chu et al.
patent: 4970152 (1990-11-01), Ashida et al.
patent: 5047353 (1991-09-01), Tsuchiya et al.
patent: 5155032 (1992-10-01), Tanaka et al.
patent: 5179006 (1993-01-01), Matuura et al.
patent: 5266461 (1993-11-01), Tanka
de Gruyter, Concise Encyclopedia of Biochemistry, Berlin, 1983, p. 125.
Clinica Chimica Acta, vol. 149, 1985, pp. 55-65, "A New Chromogenic Endotoxin-Specific Assay Using Recombined Limulus Coagulation Enzymes And Its Clinical Applications", Taminori Obayashi et al.

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