Reagent for determination of acid phosphatase

Details Reagent for determination of acid phosphatase Reagent for determination of acid phosphatase

1987-04-14

1991-01-08

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435 4, C12Q 142

Patent

active

049835122

ABSTRACT:
A reagent for the determination of acid phosphatase in body fluids which contains as a substrate a compound of the formula: ##STR1## wherein X is a halogen atom, and n and m are each an integer of 1 to 4, and a method for the determination of acid phosphatase in body fluids using the reagent. The reagent is clinically useful for diagnosis of prostate diseases such as prostate carcinoma and prostatomegaly and observation of progress thereof.

REFERENCES:
Faith et al., Chemical Abstracts, vol. 70:3538n, No. 1 (1969).
Lorentz et al., Enzyme, vol. 20, pp. 248-256 (1975).
Kanejima et al., Chemical Abstracts, vol. 107:129964z (1987).
Kirby et al. (1), Journal of the American Chemical Society, vol. 89(20, pp. 415-423 (1967).
Kirby et al. (2), Journal of the Chemical Society, pp. 135-141 (1968).
de Jongh et al., RECUEIL, vol. 87, pp. 1327-1338 (1968).

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