Chemistry: analytical and immunological testing – Biological cellular material tested
Patent
1994-02-18
1995-11-28
Redding, David A.
Chemistry: analytical and immunological testing
Biological cellular material tested
436 18, 436166, 436811, G01N 3348
Patent
active
054707510
ABSTRACT:
A reagent for staining malaria infected cells and a method for detecting malaria infected cells using the same, wherein the regent is a staining solution comprising at least one first dye of an Auramine analogue having the formula (I): ##STR1## wherein R.sub.1 to R.sub.6 represents a hydrogen atom, or a methyl or ethyl group, X.sub.1 represents a halogen atom, and at least one second dye of a condensed benzene derivative having the formula (II): ##STR2## wherein A represents ##STR3## R represents a C.sub.1-6 alkyl group, X.sub.2 represents a halogen atom, Y represents --CH.dbd. or --NH--, n represents 0 or 1, and B represents ##STR4## or a phenyl group substituted with 2 lower alkoxy group or with 1 di-lower alkylamino group. A test sample is treated with reagent to stain malaria infected cells. The stained malaria infected cells are then optically detected.
REFERENCES:
patent: 4971917 (1990-11-01), Kuroda
patent: 4981803 (1991-01-01), Kuroda
patent: 4985171 (1991-01-01), Kuroda et al.
patent: 4985174 (1991-01-01), Kuroda et al.
Database WPI, Section Ch, Week 8712, Derwent Publications Ltd., Reticulocyate Determination Using Flow . . . , Feb. 1987.
van Vianen et al., Cytometry, Flow Cytometric Screening of Blood . . . , vol. 14, pp. 276-280, 1993.
Pattanapanyasat et al., Cytometry, Two-Color Flow Cytometric Analysis . . . , vol. 14(4), pp. 449-454, 1993.
Rickman et al., The Lancet, Rapid Diagnosis of Malaria By . . . , vol. 1989, pp. 68-71, 1989.
Pattanapanyasat et al., Cytometry, Flow Cytometric Two-Color . . . , vol. 13, pp. 182-187, 1992.
Jacobberger et al., Cytometry, Analysis of Malaria Parasite-Infected . . . , vol. 4, pp. 228-237, 1983.
J. M. Whaun et al., Cytometry, Rapid Identification and Detection of . . . , vol. 4, No. 2, pp. 117-122, 1983.
M. T. Makler et al., Cytometry, Thiazole Orange: A New Dye . . . , vol. 8, pp. 568-570.
"Rinshokensa" vol. 23, No. 4.
"Rinshokensa" 32(7)--1988, pp. 803-806.
"Cytometry" 4:117-122 (1983).
"Cytometry" 8:568-570 (1987).
"Cytometry" 4:228-237 (1983).
"Cytometry" 13:182-187 (1992).
Matsumoto Hideaki
Sakata Takashi
Redding David A.
TOA Medical Electronics Co., Ltd.
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