Chemistry: analytical and immunological testing – Clotting or clotting factor level tests
Patent
1993-11-18
1995-03-28
Warden, Robert J.
Chemistry: analytical and immunological testing
Clotting or clotting factor level tests
436 16, 436 18, 436 71, 435 2, 435 13, 435214, 2524081, 530381, 530382, 530384, G01N 3386
Patent
active
054016630
ABSTRACT:
A reagent blood coagulation that causes an increase in turbidity changes when added to a plasma sample containing a substance activating coagulation factor activating such as tissue thromboplastin, phospholipid and thrombin, calcium ion, and molecular substance such as high molecular vinyl and a high molecular polysaccharide. By adding a molecular substance to the reagent, the turbidity change due to blood coagulation is increased, and hence the changing quantity of transmitted light or scattered light increases, thereby making it possible to achieve a more accurate detection. Besides, by adjusting the electric conductivity, pH and osmotic pressure to proper values, the turbidity change due to blood coagulation may be further amplified.
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Bhat N.
TOA Medical Electronics Co., Ltd.
Warden Robert J.
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