Reagent delivery apparatus and methods

Chemistry: analytical and immunological testing – Including sample preparation – Volumetric liquid transfer

Reexamination Certificate

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Details

C422S501000, C422S509000, C422S519000, C422S524000, C073S864010, C073S864220, C073S864240, C073S864250

Reexamination Certificate

active

07955865

ABSTRACT:
Apparatus for dispensing droplets of reagent onto samples includes a probe tip to which droplets of reagent can adhere. The apparatus advances the probe tip toward a sample until a droplet of reagent touches the sample and is pulled off from the probe tip. A sensor detects that the droplet has been pulled off from the probe tip and halts the advance of the probe tip before the probe tip touches the sample. Such apparatus may be used to automatically dispense small volumes of reagent onto fragile samples.

REFERENCES:
patent: 4661368 (1987-04-01), Rohde et al.
patent: 4737344 (1988-04-01), Koizumi et al.
patent: 4762578 (1988-08-01), Burgin, Jr. et al.
patent: 4794085 (1988-12-01), Jessop et al.
patent: 5143849 (1992-09-01), Barry et al.
patent: 2001/0049148 (2001-12-01), Wolk et al.
International Search Report for PCT/CA2005/000897, International Searching Authority, Oct. 6, 2005, pp. 1-5.

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