Reagent and test kit for determining glycosylated hemoglobin

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Sample mechanical transport means in or for automated...

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Details

23230B, 23913, 252408, 424 11, G01N 3372

Patent

active

042553857

ABSTRACT:
A method, reagent and test kit for determining glycosylated hemoglobin in blood samples which involves liberating hemoglobins from red blood cells by chemical or physical means and reacting non-glycosylated hemoglobin with an allosteric site binding substance which reacts with the allosteric binding site of non-glycosylated hemoglobin and thereby alters the distribution between allosteric forms of the hemoglobins and measuring the change. This method is useful in monitoring glucose metabolism for detecting and controlling diabetes.

REFERENCES:
"Gradwohl's Clinical Laboratory Methods and Diagnosis," S. Frankel et al., Eds., vol. 1, pp. 403, Seventh Edition, C. V. Mosby Co., Saint Louis, 1970.

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