Surgery – Diagnostic testing – Respiratory
Reexamination Certificate
2005-05-10
2005-05-10
Nasser, Robert L. (Department: 3736)
Surgery
Diagnostic testing
Respiratory
C073S023300, C422S084000
Reexamination Certificate
active
06890305
ABSTRACT:
The present invention relates to an assay for evaluating alveolar exchange of oxygen. A13C-labeled substrate, such as13C-sodium bicarbonate is administered to a subject by oral or iv intake, and exhaled13CO2is measured. The13CO2in expired breath can be collected at various time points following administration of the substrate and measured in Δ per mil with a mass analyzer or photometer, such as an IR spectrometer. This process can be used as a diagnostic test for the indication of, treatment and/or evaluation of the severity of respiratory tract diseases or infections.
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Irie Yasuo
Modak Anil S.
Cambridge Isotope Laboratories
Finnegan Henderson Farabow Garrett & Dunner L.L.P.
Nasser Robert L.
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