Chemistry: analytical and immunological testing – Biological cellular material tested
Patent
1995-06-29
1998-07-28
Wallenhorst, Maureen M.
Chemistry: analytical and immunological testing
Biological cellular material tested
436 8, 436 10, 436 17, 436 66, 436164, 436166, 436172, 436175, 436176, 435 2, G01N 3348
Patent
active
057862249
ABSTRACT:
A lytic reagent composition is provided which selectively stromatolyses red blood cells in a blood sample. In addition, a lytic reagent system is provided which enables the differentiation of at least three subpopulations of leukocytes. A method for using the lytic reagent system is also provided. Still further, the lytic reagent system finds use in the determination of the hemoglobin in the blood. The lytic reagent system utilizes an alkyl sulfate, polyoxyethylene based surfactant and acid with a hypertonic, alkaline, stabilizing reagent. The system and analysis method maintains the cellular morphology of the leukocytes and can be used to analyze normal and abnormal blood samples, fresh and aged blood, human and non-human animal blood samples.
REFERENCES:
patent: 4286963 (1981-09-01), Ledis et al.
patent: 4485175 (1984-11-01), Ledis et al.
patent: 4853338 (1989-08-01), Benezra et al.
patent: 4978624 (1990-12-01), Cremins
patent: 5116539 (1992-05-01), Hamaguchi et al.
patent: 5125737 (1992-06-01), Rodriquez et al.
patent: 5155044 (1992-10-01), Ledis et al.
patent: 5196346 (1993-03-01), Lefevre et al.
patent: 5232857 (1993-08-01), Lefevre et al.
patent: 5242832 (1993-09-01), Sakata
patent: 5250437 (1993-10-01), Toda et al.
patent: 5389549 (1995-02-01), Hamaguchi et al.
patent: 5496734 (1996-03-01), Sakata
patent: 5518928 (1996-05-01), Cremins
patent: 5538893 (1996-07-01), Sakata et al.
patent: 5677183 (1997-10-01), Takarada et al.
patent: 5686308 (1997-11-01), Li et al.
Oshiro, Iwao, et al, Clin. Biochem., 15 (1) 83-88 (1982), "New Metod for Homoglobin Determination by Using Sodium Lauryl Sulfate (SLS)".
Fischer Timothy J.
Li Yi
Young Carole
Alter Mitchell E.
Coulter Corporation
Wallenhorst Maureen M.
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