Reagent

Details Reagent Reagent

1996-02-26

1998-09-08

Leary, Louise N.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving glucose or galactose

435 16, 435 12, 435 26, 435 25, 435 4, 435963, C12Q 154, C12Q 152, C12Q 132, G01N 3353

Patent

active

058044027

ABSTRACT:
This invention relates to a reagent for enzymatic determination of an analyte concentration in a patient wherein the degree of oxidation of a coenzyme is measured, characterized in that said reagent is stabilized against oxidation by a coenzyme reduction system comprising an enzyme and substrate pair selected so as to enable continuous regeneration of said coenzyme throughout storage of said reagent. Also disclosed is an improvement in an enzymatic method of determination of an analyte concentration in a sample body fluid wherein the degree of oxidation of a coenzyme is measured, the improvement comprising stabilizing a reagent comprising said coenzyme against oxidation by a coenzyme reduction system comprising an enzyme and substrate pair selected so as to enable continuous regeneration of said coenzyme throughout storage of said reagent. Also disclosed are reagents for the determination of aspartate aminotransferase, alanine aminotransferase, ammonia and urea.

REFERENCES:
patent: 3956069 (1976-05-01), Allain et al.
patent: 4153511 (1979-05-01), Modrovich
patent: 4310624 (1982-01-01), Modrovich
patent: 4394449 (1983-07-01), Modrovich
patent: 5116728 (1992-05-01), Crowther et al.

Affiliated with

Also associated with

Rating

Reagent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Reagent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reagent will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1281126