Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Patent
1994-08-15
1996-01-23
Webman, Edward J.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
424465, 424468, 424409, 514960, 514961, A61K 922, A61K 910, A61K 4736
Patent
active
054863643
ABSTRACT:
A solid dosage form, such as a pharmaceutical tablet, containing a rapidly hydratable konjac glucomannan sustained release excipient such as clarified konjac, cryogenically ground konjac and plasticized konjac. The method of making the tablets by compressing excipient and pharmaceutically active ingredient as dry powders.
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patent: 4994276 (1991-02-01), Baichwal et al.
patent: 5096714 (1992-03-01), Kuhrts
"Formulating For Controlled Release with Methocel Cellulose Ethers", Bulletin of Dow Chemical Company (1987).
Chronotherapeutic Release from Direct Compression Tablets Using Heterodisperse Polysaccharides, Stainforth, et al. extended Abstract of Paper presented at AAPS Meeting, Washington, D.C. pp. 18-21, 1991.
Preparatin and Dissolution Characteristics of Pullulan Tablets Ohta, et al., Kobunshi Ronbunshu, vol. 42, No. 11, pp. 817-823 (Nov. 1985).
Konjac Flour and Properties and Applications, Richard J. Tye, Food Technology (Mar. 1991).
Erkoboni David F.
King Victor L.
Wheatley Thomas A.
Andersen Robert L.
Cupoli Anthony L.
FMC Corporation
Greenfield Mark A.
Webman Edward J.
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