Reactor/separator device for use in automated solid phase immuno

Chemistry: physical processes – Physical processes – Crystallization

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232306, 23915, 23920, 2101981, 422 72, 424 1, 424 12, 435 7, G01N 3316, G01N 3106

Patent

active

042446945

ABSTRACT:
A reactor/separator device is provided for use in automated solid phase immunoassay. The device is a column, fitted at the bottom portion thereof with a water impermeable disc which can hold immunoabsorbents immobilized antisera, ion exchange resins and the like. When the contents of the column supported by the disc are brought into contact with an aqueous phase containing reagents or reactants by centrifugal force, a chemical reaction is initiated. After reaction, centrifugally applied pressure forces the aqueous phase through the filter disc making it water permeable and separating a desired component for subsequent analysis.

REFERENCES:
patent: 3918909 (1975-11-01), Arlman
patent: 3953172 (1976-04-01), Shapiro
patent: 3961894 (1976-06-01), Gordon
patent: 4039652 (1977-08-01), Adams
patent: 4059685 (1977-11-01), Johnson
patent: 4128628 (1978-12-01), Brooker
patent: 4151254 (1979-04-01), Gimovsky
patent: 4170454 (1979-10-01), Meriadec
G. Ertingshausen et al., Clin. Chem., 21(9), 1305-1313, (1975).

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