Reaction tray for membrane hybridizations

Chemistry: molecular biology and microbiology – Miscellaneous

Patent

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Details

435285, C12M 100

Patent

active

048227420

ABSTRACT:
A reaction tray specially suited for membrane hybridizations is disclosed. A tray 102 manufactured of firm but inexpensive material has a flat bottom. A firm but flexible overlay 106 is placed atop a membrane to evenly distribute a freely diffusing reactant, hinder evaporation, and avoid contamination. A lid 104 is friction fit onto the tray 102. The tray assembly 102/104/106 is floated on a water bath for the duration of the hybridization reaction. Manual handling of dangerous reactants and the delicate membrane is minimized. Low manufacturing costs allow the tray assembly to be disposable after a single use.

REFERENCES:
patent: 3726767 (1973-04-01), White
patent: 3745091 (1973-07-01), McCormick
patent: 4294924 (1981-10-01), Pepicelli et al.
patent: 4321330 (1982-03-01), Baker et al.
patent: 4596695 (1986-06-01), Cottingham
patent: 4598050 (1986-07-01), Brown
patent: 4634676 (1987-01-01), Sapatino

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