Chemical apparatus and process disinfecting – deodorizing – preser – Shock or sound wave – Including supersonic or ultrasonic energy generation means
Patent
1996-12-07
1998-07-14
Tran, Hien
Chemical apparatus and process disinfecting, deodorizing, preser
Shock or sound wave
Including supersonic or ultrasonic energy generation means
422 63, 422 65, 4352873, 436177, 436809, B06B 100
Patent
active
057799857
ABSTRACT:
An apparatus for facilitating the running of multiple simultaneous solid phase reactions for mounting on a temperature controllable water bath and a method of using this apparatus in the presence or absence of paramagnetic beads to perform chemical syntheses resulting in separation and recovery of a final desired reaction product is provided. The apparatus comprises a reaction plate, a reaction vessel for mounting in the reaction plate, a reaction plate holder, a screw-like rod, a mounting block attached to the reaction plate holder for operably receiving the screw-like rod, a motor, a sonication region in the water bath and a magnetic separation region in the water bath. Paramagnetic beads having reaction sites are introduced into the reaction vessels along with the appropriate solvent and one or more reactants. The contents of the reaction vessel are sonicated, then moved to the magnetic separation region where the paramagnetic beads are tightly held against the reaction vessel while the solvent is aspirated off. Once the desired reaction product is attained, the reaction product is cleaved off the paramagnetic bead. In an alternative embodiment, chemical synthesis is performed in a similar manner in the absence of the paramagnetic beads.
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Cohen Jerry
Erlich Jacob N.
Solid Phase Sciences Corporation
Tran Hien
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