Reaction monitoring of chiral molecules using fourier...

Chemistry: analytical and immunological testing – Optical result – Spectrum analysis

Reexamination Certificate

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C356S051000, C422S082050, C422S082090, C422S082110, C436S091000, C436S103000, C436S106000, C436S119000, C436S124000, C436S127000, C436S139000

Reexamination Certificate

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07378283

ABSTRACT:
A method and apparatus to monitor the enantiomeric excess of chiral molecules participating in a chemical reaction. The method includes real time monitoring of the chemical reaction by obtaining a VCD spectra and an IR spectra of the chemical compounds in the reaction, and manipulating the spectra to obtain a % EE value. Using such real time information, the reaction parameters can be changed to shift the reaction to produce more of one chiral molecule than another.

REFERENCES:
patent: 6480277 (2002-11-01), Nafie
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