Optics: measuring and testing – Range or remote distance finding – With photodetection
Patent
1975-04-07
1976-11-02
Corbin, John K.
Optics: measuring and testing
Range or remote distance finding
With photodetection
23230B, 356201, G01J 342, G01N 2100
Patent
active
039893839
ABSTRACT:
A system for detecting the reaction rate of change of a solution. Enzyme activity of a sample may be measured by such a system. In the system, the light transmittance characteristic of the sample changes in accordance with the reaction change. Detection circuitry detects the variation in light absorbance and develops an electrical signal which varies in accordance with the absorbance, thus varying in accordance with the reaction change. First sampling circuitry samples the electrical signal at predetermined first intervals and develops a first sampling signal during that sampling which is proportional to the electrical signal. This first sampling signal is held in the first sampling circuitry until the following sampling. Second sampling circuitry samples the first sampling signal at predetermined intervals and develops a second sampling signal during the sampling which is proportional to the first sampling signal. The second sampling signal is held in the second sampling circuitry until the following sampling. The first and second sampling signals are summed to develop an output signal which represents the difference between the first and second signals and is therefore an indication of the reaction rate of change between sampling intervals. A scaling factor is added to this output signal for converting the signal into known and recognized units such as optical absorbance and the converted signal is displayed on a display device.
REFERENCES:
patent: 3701601 (1972-10-01), Plumpe, Jr. et al.
patent: 3810696 (1974-05-01), Hutchins, Jr.
patent: 3881992 (1975-05-01), Ralston
Bio-Technology Instruments Corporation
Corbin John K.
Hille Rolf
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